ORTHOSIA ôr thō’ zĭ ə (̓Ορθωσίας; KJV ORTHOSIAS). A city to which Trypho fled after his defeat by Antiochus VII Sidetes in the days of Simon Maccabeus (1 Macc 15:37). It was prob. located about 12 m. N of Tripoli, but is now unidentified.