Genesis 4:16-18

Amplified Bible, Classic Edition

¹⁶So Cain went away from the presence of the Lord and dwelt in the land of Nod [wandering], east of Eden.

¹⁷And Cain’s wife [one of Adam’s offspring] became pregnant and bore Enoch; and Cain built a ^[a]city and named it after his son Enoch.

¹⁸To Enoch was born Irad, and Irad was the father of Mehujael, and Mehujael the father of Methusael, and Methusael the father of Lamech.

Genesis 4:17 C.H. Dodd (cited by Adam Clarke, The Holy Bible with A Commentary) shows that it would have been possible for Adam and Eve, in the more than 100 years he estimates may have elapsed since their union, to have had over 32,000 descendants at the time Cain went to Nod, all of them having sprung from Cain and Abel, who married their sisters.